A diaminopyrimidine dihydrofolate reductase inhibitor being developed for the treatment of skin and tissue infections caused by antibioticresistant bacteria. Iclaprim works in a different way than most other antibiotics and rapidly kills bacteria. Dec 01, 2003 consistent with the selective inhibition of dhfr by iclaprim and tmp is the observation that both compounds preferentially inhibit dna and rna synthesis with little or no effect on cell wall or protein synthesis even at high concentrations. We thrive on community collaboration to help us create. Mina guirguis is a registered australian business name with the australian business.
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